Mean cost of bringing new drug to US market Is $879.3 million
Jul 02, 2024
R&D has remained relatively stable among large pharma companies despite a 27.3% growth in sales.
10 percent of new drugs approved without meeting primary efficacy end points
Feb 14, 2023
The findings were seen for 21 drug approvals between 2018 and 2021, with only one-third needing postmarketing studies.
Risk for dementia similar with SGLT2 inhibitors, dulaglutide in T2DM
Aug 26, 2024
The estimated risk difference varied from −2.45 to 0.63 percentage points with SGLT2 versus dulaglutide among older adults.
Semaglutide-linked suicidal ideation ID’d in disproportionality analysis
Aug 21, 2024
Significant disproportionality was detected for semaglutide-associated suicidal ideation as an adverse drug reaction.
Commonly prescribed antibiotics linked to cutaneous adverse drug reactions
Aug 12, 2024
Sulfonamide antibiotics and cephalosporins are most strongly associated with serious cADRs relative to macrolides.
PREVENT equations reclassify half of US adults to lower ASCVD risk
Aug 02, 2024
A considerable decrease was estimated in US adults receiving or recommended for preventive treatment with statins and antihypertensives.
Pharmacist prescribing can reduce stroke risk in A-Fib patients
Aug 01, 2024
The findings were seen for pharmacist prescribing compared with usual care in older adults at high risk for stroke.
Methotrexate beneficial for reducing pain, stiffness in knee osteoarthritis
Jul 31, 2024
Significant pain reduction was seen in favor of methotrexate; stiffness and function improved at six months.
FDA warns of accidental overdoses from compounded versions of Ozempic
Jul 30, 2024
(HealthDay News) — People taking compounded versions of Ozempic have been overdosing on the drug, the US Food and Drug Administration warns. These ODs typically are due to miscommunications or miscalculations...
Extended-release oral ketamine effective for treatment-resistant depression
Jul 17, 2024
Excellent tolerability was seen, with no changes in blood pressure, minimal reports of sedation and minimal dissociation.