Mean cost of bringing new drug to US market Is $879.3 million
Jul 02, 2024
R&D has remained relatively stable among large pharma companies despite a 27.3% growth in sales.
1999 to mid-2000s saw increase in seniors using prescription meds
Jul 09, 2024
Polypharmacy increased, peaking at 43.0% in 2017 to March 2020; hyperpolypharmacy increased during 1999-2000 to 2007-2008.
Medically advised aspirin use lower in 2021 than 2012 to 2017
Jun 24, 2024
Compared with 2012 to 2017, in 2021, medically advised aspirin use for primary prevention was lower (19.3 versus 27.6 to 31.2% among adults aged 60 to 69 years; 30.6 versus 38.35 to 41.6% among those aged...
Fewer adults eligible for statins with PREVENT equations
Jun 21, 2024
Compared with the pooled cohort equations, the mean estimated 10-year ASCVD risk was lower using the PREVENT equations across all age, sex and racial subgroups, with the largest difference seen for Black...
Reteplase superior to alteplase within 4.5 hours of ischemic stroke
Jun 20, 2024
Reteplase was more likely to result in excellent functional outcome than alteplase for ischemic stroke within 4.5 hours of symptom onset.
Low-dose direct oral anticoagulants tied to more bleeding episodes
Jun 19, 2024
The findings compared with standard doses in patients with atrial fibrillation.
Endocrine Society, June 1-4
Jun 20, 2024
The conference highlighted recent advances in the diagnosis and management of obesity, endocrine disorders, diabetes, and growth hormone and thyroid diseases.
Semaglutide cuts risk for kidney outcomes, death in CKD with T2DM
May 31, 2024
A reduction was seen in risk for clinically important kidney outcomes and death from cardiovascular causes.
Semaglutide boosts kidney outcomes with obesity + cardiovascular disease
May 28, 2024
At the prespecified 104-week time point, semaglutide was associated with a lesser decline in eGFR than placebo.
Antihypertensives linked to eczematous dermatitis in seniors
May 24, 2024
The largest effect sizes were seen for diuretics and calcium channel blockers, and the smallest were seen for ACE inhibitors and beta-blockers.