In clinical trials, donanemab (Kisunla) modestly slowed the pace of thinking declines among patients in the early stages of the memory-robbing disease. But it also carried significant safety risks, including...
Risk for adverse outcomes increased with antipsychotic use in dementia
Apr 19, 2024
Risks increased for stroke, venous thromboembolism, myocardial infarction, heart failure, fracture, pneumonia and acute kidney injury.
Nearly 7 million Americans have Alzheimer’s, and caregivers are stressed
Mar 20, 2024
Nearly 7 million American seniors are living with Alzheimer’s dementia, placing a huge strain on both personal caregivers and the US healthcare system, according to a new Alzheimer’s Association...
Study IDs proportion of dementia cases attributable to known risk factors
Jan 19, 2024
The population-attributable fraction for nongenetic risk factors combined is similar for men and women, but it varies across racial and ethnic groups.
Patients with dementia less likely to receive intensive care after hospital transfer
Jan 04, 2024
The authors say that future work should focus on determining whether transfers are needed.
Coronary heart disease, especially with early onset, linked to dementia
Nov 29, 2023
A younger age of onset was linked to higher risks for incident all-cause dementia, Alzheimer’s disease and vascular dementia.
Earlier onset of A-Fib linked to risk of developing all-cause dementia
Nov 10, 2023
Younger age at A-Fib onset was linked to increased risks of all-cause and vascular dementia and Alzheimer disease.
Stress, depression linked to MCI, Alzheimer’s disease
Oct 20, 2023
Chronic stress and depression are independent risk factors and have an additive effect when combined.
High risk for psychiatric disorders seen before dementia diagnosis
Oct 20, 2023
The findings were consistent regardless of dementia subtype.
Panel of 48 CSF proteins complements existing Alzheimer’s biomarkers
Sep 07, 2023
The CSF 48 panel plus existing biomarkers significantly improved the diagnostic performance for the outcomes studied.