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The authors say the findings show a role for microbiome and the development of long COVID symptoms.
Drug was approved on an ‘accelerated’ schedule due to pressing medical need
The newly approved medication lowers the need for amputation of fingers or toes.
The highest rate increases were seen in white and Native American or Alaskan Native individuals and in the Midwest and nonmetro areas.
The findings were seen among older adults with stage 3 to 4 disease with no prior atherosclerotic cardiovascular disease.
Use was more likely among unmarried or unpartnered adults and those consuming alcohol.
Metabolic agents were the most costly category; antidiabetic agents were the mostly costly therapeutic area.
Agency’s action could widen access to the drug if more insurance companies decide to cover it
Baseline CRP, Clinical Disease Activity Index and glucocorticoid dose predict resistance to CDAI-low disease activity achievement.
Poorer outcomes were seen for 30-day sustained clinical response and 14-day initial cure rates.