Gabapentinoids linked to increased risk for severe exacerbation in COPD
Jan 16, 2024
Compared with matched nonusers, gabapentinoid users have an increased risk across indications of epilepsy, neuropathic pain and other chronic pain.
Paxlovid not helpful for reducing most post-COVID-19 conditions
Oct 31, 2023
No differences were seen in most post-COVID-19 conditions examined individually or by organ system, apart from a lower combined risk for venous thromboembolism and pulmonary embolism.
Ketamine no better than placebo for depression
Oct 25, 2023
Intravenous ketamine delivered during surgical anesthesia has no greater effect than placebo in reducing severity of depression.
Even five years postapproval, many drug studies remain nonpublic
Sep 01, 2023
The authors urge greater transparency of study results for drugs approved by the FDA.
Study looks at links between anxiety disorders, benzodiazepines, dementia
Aug 14, 2023
Benzodiazepines and anxiety disorders were linked to dementia risk, but no additional risk was seen for benzodiazepines in patients with anxiety disorders.
High-concentration capsaicin patch can cut neuropathic pain intensity
Feb 07, 2024
During high-concentration capsaicin patch treatment, a significant decrease was seen in average daily morphine equivalent dose.
Solanezumab does not slow cognitive decline in preclinical Alzheimer’s disease
Jul 19, 2023
The mean change in Preclinical Alzheimer Cognitive Composite score not significantly different at 240 weeks with solanezumab or placebo.
Limiting acetaminophen dose in combo medications beneficial
Mar 13, 2023
Limiting acetaminophen in prescription acetaminophen and opioid products is linked to a reduction in the rate of hospitalization and proportion of acute liver failure cases.
Prescription opioids linked to increased risk for serious fall events
Feb 20, 2024
The findings seen among adults of all ages, especially those aged 85 years or older; the risk was highest in the first 28 days after initiation.
Risk profile IDs COVID-19 patients who will benefit from baricitinib
Feb 26, 2024
Baricitinib plus remdesivir was linked to a reduced risk of death and progression to invasive mechanical ventilation.