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Greater healthy lifestyle increases the odds of reaching 100 years of age by 60%.
Older age, female sex and progression to symptomatic Alzheimer’s disease were associated with driving cessation.
The risk for cognitive impairment and stroke was lower with the intake of unprocessed, minimally processed foods.
No association was seen between improvements in cardiometabolic risk factors and cognition.
Neither the strength nor the significance of the association was changed when common dementia-related brain pathologies were included in the model.
The findings were seen for adherence to the Dietary Approaches to Stop Hypertension diet.
The authors say that clinical trials should consider environmental exposures and injustices.
The association was independent of Aβ and tau and accounted for 10% of the variance in cognitive decline.
Earlier menopause and higher vascular risk were synergistically associated with lower cognitive scores at follow-up.
Chronic stress and depression are independent risk factors and have an additive effect when combined.