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Associations were seen with processing speed, attention, and executive function in the older UK Biobank cohort (ages 44 to 83 years).
Midlife measurements of plasma amyloid-beta may predict risk for mild cognitive impairment, dementia in late life.
Higher baseline coffee consumption also was linked to slower Aβ-amyloid accumulation during a 126-month study period, as shown on brain MRI scans.
The protective effect, however, appears to differ by race and ethnicity.
However, after diagnosis, BMI declines at the same pace in people who develop or do not develop dementia.
The associations of housework with physical function and sensorimotor performance were intensity-dependent.
Worse executive function and processing speeding were seen with consistently higher or moderate/increasing inflammation.
No association was seen for changes in immediate or delayed memory.
The benefit was not seen overall or for domain-specific cognitive function.
The findings were seen for adherence to the Dietary Approaches to Stop Hypertension diet.