Antidepressant augmentation examined in seniors with depression
Mar 06, 2023
An improvement in well-being and remission was seen with aripiprazole-augmentation of existing antidepressants.
FDA: Patients should be cautious when using online pharmacies to buy meds
Nov 18, 2022
Red flags include pharmacies that do not require a doctor’s prescription or have a licensed pharmacist to answer questions.
Gabapentinoids linked to increased risk for severe exacerbation in COPD
Jan 16, 2024
Compared with matched nonusers, gabapentinoid users have an increased risk across indications of epilepsy, neuropathic pain and other chronic pain.
Nirmatrelvir-ritonavir does not speed up alleviation of COVID-19 symptoms
Apr 05, 2024
The time to sustained alleviation of COVID-19 symptoms was not significantly shorter with nirmatrelvir-ritonavir versus placebo.
Paxlovid not helpful for reducing most post-COVID-19 conditions
Oct 31, 2023
No differences were seen in most post-COVID-19 conditions examined individually or by organ system, apart from a lower combined risk for venous thromboembolism and pulmonary embolism.
Evidence for efficacy of antidepressants for pain Is limited
Feb 02, 2023
In 11 comparisons, antidepressants were efficacious, but they were inefficacious or evidence was inconclusive for 31 comparisons.
Ketamine no better than placebo for depression
Oct 25, 2023
Intravenous ketamine delivered during surgical anesthesia has no greater effect than placebo in reducing severity of depression.
Even five years postapproval, many drug studies remain nonpublic
Sep 01, 2023
The authors urge greater transparency of study results for drugs approved by the FDA.
Study looks at links between anxiety disorders, benzodiazepines, dementia
Aug 14, 2023
Benzodiazepines and anxiety disorders were linked to dementia risk, but no additional risk was seen for benzodiazepines in patients with anxiety disorders.
Insulin out-of-pocket cost caps do not increase insulin use
Mar 26, 2024
Caps are associated with a reduction in insulin costs, mainly driven by patients enrolled in health savings accounts.