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However, protection against severe disease remains high, at 88.9%, for omicron BA.1 at 40 weeks.
Officials did not specify where the samples were from; most patients infected with new BA.2.86 variant have had mild symptoms.
A decreased use of insulin and sulfonylureas was seen postintervention.
The updated shot is expected to better target variants that are circulating now and help prevent hospitalization and death from the virus.
Patients with unrecognized need for COVID-19 therapy appear to have higher odds of readmission, regardless of race.
The chemicals already are illegal in the European Union and other places around the world.
The findings based on symptoms at 10 weeks following 15-day course in vaccinated cohort.
Changes in office systolic BP of −14.1, −13.2, −6.9 and −4.1 mm Hg were seen with 100, 50, 12.5 mg once daily of lorundrostat and placebo.
The findings were seen in older hospitalized patients with advanced chronic obstructive pulmonary disease, dementia or kidney failure.
The agency estimates that the new standard will prevent up to 4,500 premature deaths in the first year of full enforcement.