Metformin displayed a lowest risk for dementia across diverse antidiabetics, while α-glucosidase inhibitors had the highest risk.
Suicidal ideation, behaviors not increased with GLP-1 RAs for seniors with T2D
Jul 16, 2024
No significant increase was seen with the use of GLP-1 RAs versus SGLT2is or DPP4is among older Medicare beneficiaries.
Mean cost of bringing new drug to US market Is $879.3 million
Jul 02, 2024
R&D has remained relatively stable among large pharma companies despite a 27.3% growth in sales.
1999 to mid-2000s saw increase in seniors using prescription meds
Jul 09, 2024
Polypharmacy increased, peaking at 43.0% in 2017 to March 2020; hyperpolypharmacy increased during 1999-2000 to 2007-2008.
Medically advised aspirin use lower in 2021 than 2012 to 2017
Jun 24, 2024
Compared with 2012 to 2017, in 2021, medically advised aspirin use for primary prevention was lower (19.3 versus 27.6 to 31.2% among adults aged 60 to 69 years; 30.6 versus 38.35 to 41.6% among those aged...
Low-dose direct oral anticoagulants tied to more bleeding episodes
Jun 19, 2024
The findings compared with standard doses in patients with atrial fibrillation.