Fewer adults eligible for statins with PREVENT equations
Jun 21, 2024
Compared with the pooled cohort equations, the mean estimated 10-year ASCVD risk was lower using the PREVENT equations across all age, sex and racial subgroups, with the largest difference seen for Black...
Even five years postapproval, many drug studies remain nonpublic
Sep 01, 2023
The authors urge greater transparency of study results for drugs approved by the FDA.
Nursing home staff shortages tied to more inappropriate antipsychotic use
Apr 26, 2024
More inappropriate use was seen particularly for nursing homes in severely deprived neighborhoods.
Risk for dementia reduced in association with antihypertensive use
Sep 13, 2023
An individual patient data meta-analysis shows increased risk for dementia for those with untreated hypertension.
Evidence for efficacy of antidepressants for pain Is limited
Feb 02, 2023
In 11 comparisons, antidepressants were efficacious, but they were inefficacious or evidence was inconclusive for 31 comparisons.
One-quarter of older advanced cancer patients taking eight or more drugs
Mar 20, 2023
Polypharmacy was tied to an increased risk for adverse treatment outcomes, such as toxicity and early treatment discontinuation.
AHA: Semaglutide cuts risk for CVD events in patients without diabetes
Nov 14, 2023
Findings seen over three years in adults with preexisting cardiovascular disease and overweight or obesity
ACC: Semaglutide beneficial in obesity-related heart failure, type 2 diabetes
Apr 09, 2024
Larger reductions were seen in heart failure-related symptoms and physical limitations for patients with HFpEF and type 2 diabetes.
Single dose of zilebesiran linked to reduction in systolic BP
Feb 20, 2024
A significant reduction was seen in systolic blood pressure with zilebesiran 150, 300 or 600 mg once in six months and 300 mg once every three months.
Mental health treatment linked to better outcomes in CAD, heart failure
Mar 22, 2024
Patients receiving mental health treatment were less likely to be rehospitalized, have an emergency department visit or die from any cause.