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The authors say that the findings support efforts to improve social isolation and loneliness.
9,000 to 10,500 steps/day was associated with the lowest mortality risk, regardless of sedentary time.
Sedentary time was linked to higher mortality in individuals accumulating less than 22 minutes of moderate to vigorous physical activity per day.
Improvements were seen in motor and nonmotor symptoms, as well as reductions in disability and complications.
Fractures most commonly were seen in the upper extremity in women aged 65 years and older following a fall.
The findings were seen for overall accelerometer-measured physical activity and light or moderate-to-vigorous activity, as well as for steps per day.
Physical activity was tied to fewer insomnia symptoms and extreme sleep durations, both long and short.
The findings were seen even in patients with mild or previously undiagnosed disease.
Participants reported either a weekend warrior or regular physical activity pattern.
The intervention reduced sitting time at three and six months and yielded a reduction in systolic blood pressure at six months.