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The findings show a variance in associated risk with hypertension, obesity, diabetes, low HDL cholesterol and sleep disorders.
For people with diabetes, the hazard ratio for dementia was 0.46 for those with a lifestyle score of 7 versus 0 to 2.
The association was largely independent of changes in hemoglobin A1c and insulin usage.
Sulfonylurea monotherapy was linked to increased risk for all-cause dementia compared with metformin monotherapy.
The findings persisted across age, sex and comorbidities.
Chronic stress and depression are independent risk factors and have an additive effect when combined.
A mortality prediction may help guide treatment and advance care planning for community-dwelling older adults with dementia.
An increased risk was seen for atrial fibrillation and cerebrovascular disease, among others.
Some of the factors include social isolation, diabetes, heart disease, vitamin D deficiency, high C-reactive protein and low handgrip strength.
Age-standardized prevalence rates were higher among women than men, veterans than nonveterans and non-Hispanic whites.