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Dementia rates, however, were lower than a comparison cohort of people with Parkinson’s disease.
Individuals with a higher adherence to a Mediterranean diet had up to a 23% lower risk for dementia, regardless of their genetic risk.
Earlier menopause and higher vascular risk were synergistically associated with lower cognitive scores at follow-up.
Older adults with Alzheimer’s disease and related dementia have lower rates of home discharge and higher mortality.
Participants in a high versus low routine task intensity group had a higher risk for mild cognitive impairment and dementia.
Lowering blood pressure with antihypertensive treatment may reduce the risk for incident dementia in older adults with a history of hypertension.
To a lesser extent, engagement in creative artistic activities and passive mental activities were linked to lower dementia risk.
Lower percentage of patients at clinic self-identified as Black compared with average percentage living in catchment area
Similar findings were seen in a a subcohort of participants with APOE-ε4 genetic data and in an external validation cohort.
Additionally, participation was tied to greater retention of subsequent fluid intelligence.