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An increase was seen in physically and mentally unhealthy days during past month, years of life lost and age-adjusted all-cause mortality rate.
An increased risk was seen for atrial fibrillation and cerebrovascular disease, among others.
The findings show a 14% decreased colorectal cancer mortality over 14 years.
“Forever chemicals” are tied to a host of health issues and are slow to degrade in the environment.
Annual screening from age 40 to 79 appears to provide the greatest benefit and lowest risk.
The authors say that the findings support efforts to improve social isolation and loneliness.
Racial and ethnic disparities, however, persisted for various cancers, including prostate, male lung and bronchus, and female colorectal cancer.
Individuals with elevated C-reactive protein at 1.0 mg/dL and poverty had a greater risk for 15-year all-cause mortality.
At 30 days after discharge, the mortality rate was 3.2% and skilled nursing facility use rate was 2.6%.
Greater racial and geographic disparities in cancer mortality were seen for those younger than 65 years versus 65 years of age or older.