Risk for adverse outcomes increased with antipsychotic use in dementia
Apr 19, 2024
Risks increased for stroke, venous thromboembolism, myocardial infarction, heart failure, fracture, pneumonia and acute kidney injury.
Distance to neurologist, PCP may explain Alzheimer’s disease disparities
Apr 05, 2024
Non-Hispanic American Indian and/or Alaska Native and Hispanic decedents have to travel further to neurologist than non-Hispanic whites.
Higher education may protect functioning with Alzheimer’s disease
Apr 03, 2024
The findings were seen among African American individuals, with greater protective effect in APOE ɛ4 noncarriers.
Neurological conditions ranked as leading cause of disability-adjusted life years globally
Mar 15, 2024
Between 1990 and 2021, there was an 18.2 percent increase in the global DALY counts attributed to those conditions
FDA delays decision on new Alzheimer’s drug
Mar 08, 2024
Instead of approving the new Alzheimer’s drug donanemab this month, as was expected, the U.S. Food and Drug Administration will now require the experimental medication be scrutinized more closely...
Timing of CSF biomarker divergence for Alzheimer’s disease, normal cognition varies
Feb 21, 2024
Estimated times of divergence of cerebrospinal fluid biomarkers vary from 18 years for Aβ42 to six years for cognitive decline.
Lower Alzheimer’s risk seen with PDE5i initiation for erectile dysfunction
Feb 08, 2024
The greatest reduction in risk was seen for those receiving 21 to 50 phosphodiesterase type 5 inhibitor prescriptions.
Monoclonal antibodies provide small benefits in Alzheimer’s disease
Jan 26, 2024
Harms include increased risks for amyloid-related imaging abnormalities (ARIA)-edema, ARIA-hemorrhage and symptomatic ARIA-edema.
Study IDs proportion of dementia cases attributable to known risk factors
Jan 19, 2024
The population-attributable fraction for nongenetic risk factors combined is similar for men and women, but it varies across racial and ethnic groups.
Transcranial direct current stimulation beneficial in Alzheimer’s disease
Dec 07, 2023
Active tCDS improves cognitive functions in memory domain, including word recall, recall of test instructions and word recognition.